Comparison of adverse health effect, safety issue and regulation of Download Scientific Diagram HealthMatch Vaping may be safer than cigarettes, but it's not safe Fast facts on the effects of e cigarettes and vaping Nonnicotine vapes may be marketed as safe, but many still contain chemicals, have unknown health effects, and aren't FDAregulated. Teens are using them more ofteneven alongside nicotine vapes. No ecigarette is risk free.